- 专利标题： Use of type-B lantibiotic-based compounds having antimicrobial activity
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申请号： US12357077申请日： 2009-01-21
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公开(公告)号： US08183202B2公开(公告)日： 2012-05-22
- 发明人: Sjoerd Nicolaas Wadman , Michael John Dawson , Jesus Cortes Bargallo
- 申请人： Sjoerd Nicolaas Wadman , Michael John Dawson , Jesus Cortes Bargallo
- 申请人地址： GB Hertfordshire
- 专利权人： Novacta Biosystems Limited
- 当前专利权人： Novacta Biosystems Limited
- 当前专利权人地址： GB Hertfordshire
- 代理机构： Morgan, Lewis & Bockius LLP
- 优先权： GB0714030.4 20070718
- 主分类号： A61K38/12
- IPC分类号： A61K38/12 ; C07K7/64
摘要：
A method for the treatment or prophylaxis of a microbial infection of the lower intestine or colon in a subject is described, wherein the method comprises administration to the subject of a type-B lantibiotic, wherein the type-B lantibiotic may include compounds selected from the group consisting of mersacidin, actagardine, plantaricin, planosporicin, ruminococcin, antibiotic 10789, michiganin and haloduracin, and derivatives and variants thereof.
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