发明授权
- 专利标题: Triazole compounds that modulate HSP90 activity
- 专利标题(中): 调节HSP90活性的三唑化合物
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申请号: US11807331申请日: 2007-05-25
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公开(公告)号: US08183384B2公开(公告)日: 2012-05-22
- 发明人: Dinesh U. Chimmanamada , Weiwen Ying , Teresa Przewloka , Shijie Zhang , Kevin Foley , Zhenjian Du , Dan Zhou , Shuzhen Qin
- 申请人: Dinesh U. Chimmanamada , Weiwen Ying , Teresa Przewloka , Shijie Zhang , Kevin Foley , Zhenjian Du , Dan Zhou , Shuzhen Qin
- 申请人地址: US MA Lexington
- 专利权人: Synta Pharmaceuticals Corp.
- 当前专利权人: Synta Pharmaceuticals Corp.
- 当前专利权人地址: US MA Lexington
- 代理机构: McCarter & English LLP
- 代理商 Steven G. Davis
- 主分类号: C07D249/12
- IPC分类号: C07D249/12 ; A61K31/4196
摘要:
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.
公开/授权文献
- US20080004277A1 Triazole compounds that modulate HSP90 activity 公开/授权日:2008-01-03
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