A multi-panel display device and a method of driving the same, which can simplify a driving circuit for driving multiple flat panel display devices, thereby decreasing the fabrication cost, are disclosed. In the device configured of an alignment of multiple flat panel display devices for representing a single image, the device comprises multiple flat panel display devices, wherein each flat panel display device includes a display panel configured of a plurality of pixel regions, a data driver driving a plurality of data lines provided in the display panel, and a timing controller receiving image data and synchronization signals from an external source so as to divide the received image data, converting a signal frequency of at least one of the synchronization signals, and converting a size of the divided image data in accordance with the frequency-converted synchronization signal, thereby providing the size-converted divided image data to the data driver.