发明授权
- 专利标题： Immunotherapeutic methods targeted toward stratum corneum chymotryptic enzyme
- 专利标题（中）： 靶向角质层糜蛋白酶的免疫治疗方法
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申请号： US12005175申请日： 2007-12-26
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公开(公告)号： US08187587B2公开(公告)日： 2012-05-29
- 发明人: Timothy J. O'Brien , Martin J. Cannon , Alessandro Santin , Kristina L. Bondurant
- 申请人： Timothy J. O'Brien , Martin J. Cannon , Alessandro Santin , Kristina L. Bondurant
- 申请人地址： US AR Little Rock
- 专利权人： Board of Trustees of the University of Arkansas
- 当前专利权人： Board of Trustees of the University of Arkansas
- 当前专利权人地址： US AR Little Rock
- 代理商 Benjamin Aaron Adler
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61K38/00 ; A61K48/00
摘要：
The present invention discloses the protease stratum corneum chymotrytic enzyme (SCCE) is specifically over-expressed in ovarian and other malignancies. A number of SCCE peptides can induce immune responses to SCCE, thereby demonstrating the potential of these peptides in monitoring and the development of immunotherapies for ovarian and other malignancies.
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