发明授权
- 专利标题: G-CSF transferrin fusion proteins
- 专利标题(中): G-CSF转铁蛋白融合蛋白
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申请号: US10575033申请日: 2004-10-08
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公开(公告)号: US08188032B2公开(公告)日: 2012-05-29
- 发明人: Wei-Chiang Shen , Yun Bai , David Ann , Adam Widera
- 申请人: Wei-Chiang Shen , Yun Bai , David Ann , Adam Widera
- 申请人地址: US MD Bethesda
- 专利权人: National Institutes of Health (NIH)
- 当前专利权人: National Institutes of Health (NIH)
- 当前专利权人地址: US MD Bethesda
- 代理机构: DLA Piper LLP (US)
- 国际申请: PCT/US2004/033337 WO 20041008
- 国际公布: WO2005/034877 WO 20050421
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; A61P7/06
摘要:
A polypeptide comprising a G-CSF domain operably linked to a Tf domain, wherein the ability of the polypeptide to be transported into a cell expressing a TfR gene or the ability of the polypeptide to be transported across a cell expressing a TfR gene via transcytosis is higher than that of the G-CSF domain alone.
公开/授权文献
- US20090042777A1 G-CSF Transferrin Fusion Proteins 公开/授权日:2009-02-12
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