发明授权
- 专利标题: Adenosine derivatives as A2A receptor agonists
- 专利标题(中): 腺苷衍生物作为A2A受体激动剂
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申请号: US12310254申请日: 2007-09-13
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公开(公告)号: US08188100B2公开(公告)日: 2012-05-29
- 发明人: Robin Alec Fairhurst , Roger John Taylor
- 申请人: Robin Alec Fairhurst , Roger John Taylor
- 申请人地址: CH Basel
- 专利权人: Novartis AG
- 当前专利权人: Novartis AG
- 当前专利权人地址: CH Basel
- 代理机构: Strain & Strain PLLC
- 代理商 Paul D. Strain, Esq.
- 优先权: EP06120706 20060914
- 国际申请: PCT/EP2007/059666 WO 20070913
- 国际公布: WO2008/031875 WO 20080320
- 主分类号: C07D519/00
- IPC分类号: C07D519/00 ; A61K31/52 ; A61P11/00 ; A61P11/06 ; A61P37/08 ; A61P17/06 ; A61P29/00 ; C07D473/40 ; C07D473/16
摘要:
A compound of formula (I), or stereoisomers or pharmaceutically acceptable salts thereof, formula (1), or stereoisomers or pharmaceutically acceptable salts thereof, wherein A, U1, U2, R1a, R1b, R2 and R3 have the meanings as indicated in the specification, are useful for treating conditions mediated by activation of the adenosine A2A receptor, especially inflammatory or obstructive airways diseases. Pharmaceutical compositions that contain the compounds and a process for preparing the compounds are also described.
公开/授权文献
- US20090325967A1 ADENOSINE DERIVATIVES AS A2A RECEPTOR AGONISTS 公开/授权日:2009-12-31
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