发明授权
- 专利标题: Piperidinyl-substituted isoquinolone derivatives
- 专利标题(中): 哌啶基取代的异喹诺酮衍生物
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申请号: US12019866申请日: 2008-01-25
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公开(公告)号: US08188117B2公开(公告)日: 2012-05-29
- 发明人: Oliver Plettenburg , Armin Hofmeister , Dieter Kadereit , Joachim Brendel , Matthias Loehn
- 申请人: Oliver Plettenburg , Armin Hofmeister , Dieter Kadereit , Joachim Brendel , Matthias Loehn
- 申请人地址: FR Paris
- 专利权人: Sanofi-Aventis
- 当前专利权人: Sanofi-Aventis
- 当前专利权人地址: FR Paris
- 代理机构: Scully, Scott, Murphy & Presser, P.C.
- 优先权: EP05016154 20050726
- 主分类号: C07D401/12
- IPC分类号: C07D401/12 ; A61K31/4725
摘要:
The invention relates to 6-piperidinyl-substituted isoquinolone derivatives of the formula (I) or isoquinoline derivatives of the formula (I′) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
公开/授权文献
- US20090093518A1 Piperidinyl-substituted isoquinolone derivatives 公开/授权日:2009-04-09