Invention Grant
US08188120B2 Lactam-containing compounds and derivatives thereof as factor Xa inhibitors
有权
含有内酰胺的化合物及其衍生物作为因子Xa抑制剂
- Patent Title: Lactam-containing compounds and derivatives thereof as factor Xa inhibitors
- Patent Title (中): 含有内酰胺的化合物及其衍生物作为因子Xa抑制剂
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Application No.: US13101536Application Date: 2011-05-05
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Publication No.: US08188120B2Publication Date: 2012-05-29
- Inventor: Donald J. P. Pinto
- Applicant: Donald J. P. Pinto
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agency: Fitzpatrick, Cella, Harper & Scinto
- Main IPC: C07D401/10
- IPC: C07D401/10 ; C07D401/12 ; A61K31/4433 ; A61P7/02
Abstract:
The present application describes lactam-containing compounds and derivatives thereof of Formula I: P4—P-M-M4 I or pharmaceutically acceptable salt forms thereof, wherein ring P, if present is a 5-7 membered carbocycle or heterocycle and ring M is a 5-7 membered carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
Public/Granted literature
- US20110212930A1 LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS Public/Granted day:2011-09-01
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