A layout structure disposed on the substrate of the liquid crystal display (LCD) for chip coupling is provided. The first and second orientations that are substantially perpendicular to the first orientation can be defined on the substrate. The layout structure includes a plurality of lines, which extend along the second orientation, and a plurality of conductive pads that are respectively disposed on the lines. The conductive pads are distributed along the first orientation and staggered along the second orientation. Each line can shift away from the adjacent conductive pad on the first orientation. Thus, the LCD chip has a better conductivity and a thinner dimension under the precision of the conventional machines.