The invention relates to a method and arrangement for managing a calculation of a destination time alignment value TA2 to be used by a user equipment in a destination cell after a handover in a radio access network. The radio access network comprises a source cell, the destination cell and a user equipment which is adapted to switch to communicate with a destination base station comprised in the destination cell after the handover. The source cell is adapted to transmit a first reference signal and the destination cell is adapted to transmit a second reference signal. The method comprises the step of obtaining a first information comprising the time difference A between a point of time when the second reference signal is transmitted and a point of time when the destination cell receives the user equipment transmission, obtaining a second information comprising the time difference C between the point of time when second reference signal is received and a point of time when the user equipment transmission is transmitted, and calculating the destination time alignment TA2, by means of the formula [TA2=C−A].