A memory device comprises a memory array, a status register, a status-register write-protect bit and a security register. The memory array contains a number of memory blocks. The status register includes at least one protection bit indicative of a protection status of at least one corresponding block of the memory blocks. The status-register write-protect bit is coupled with the status register for preventing a state change of the at least one protection bit. The security register includes at least one register-protection bit for preventing the state change in one of the at least one protection bit of the status register and the status-register write-protect bit.