A system for selecting high speed serial signals includes a loading module, a layout selecting module, a data processing module, and an output module. The loading module reads a chip package length file; a layout selecting module reads a layout file and selects high speed serial signals preset by a user; the data processing module selects pins information of a start chip and a terminal chip transmit the selected high speed serial signals and finds the chip package length information, and analyzes interrupt points of the layout character from the start chip and outputs the chip package length information of the start chip, the layout length information, and the chip package length information of the terminal chip in sequence to the output module, to convert into a table and displays the table via a display device.