发明授权
- 专利标题： Targeted antibodies directed to DLL4
- 专利标题（中）： 针对DLL4的靶向抗体
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申请号： US12562268申请日： 2009-09-18
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公开(公告)号： US08192738B2公开(公告)日： 2012-06-05
- 发明人: Vahe Bedian , David Jenkins , Ian Foltz
- 申请人： Vahe Bedian , David Jenkins , Ian Foltz
- 申请人地址： US MD Gaithersburg
- 专利权人： MedImmune, LLC
- 当前专利权人： MedImmune, LLC
- 当前专利权人地址： US MD Gaithersburg
- 代理机构： MedImmune, LLC
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/18 ; C07K14/435
摘要：
The invention relates to targeted binding agents against DLL4 and uses of such agents. More specifically, the invention relates to fully human monoclonal antibodies directed to DLL4. The described targeted binding agents are useful in the treatment of diseases associated with the activity and/or overproduction of DLL4 and as diagnostics.
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