Invention Grant
US08193181B2 Xinafoate salt of N4-(2,2-difluoro-4H-benzo[1,4]oxazin-3-one)-6-yl]-5-fluoro-N2-[3-(methylaminocarbonylmethyleneoxy) phenyl]2,4-pyrimidinediamine
有权
N4-（2,2-二氟-4H-苯并[1,4]恶嗪-3-酮）-6-基] -5-氟-N 2 - [3-（甲基氨基羰基亚甲基氧基）苯基] 嘧啶二胺
![Xinafoate salt of N4-(2,2-difluoro-4H-benzo[1,4]oxazin-3-one)-6-yl]-5-fluoro-N2-[3-(methylaminocarbonylmethyleneoxy) phenyl]2,4-pyrimidinediamine](/docs/US/2012-06-05/US08193181B2/abs.jpg.600x600.jpg)
- Patent Title: Xinafoate salt of N4-(2,2-difluoro-4H-benzo[1,4]oxazin-3-one)-6-yl]-5-fluoro-N2-[3-(methylaminocarbonylmethyleneoxy) phenyl]2,4-pyrimidinediamine
- Patent Title (中): N4-（2,2-二氟-4H-苯并[1,4]恶嗪-3-酮）-6-基] -5-氟-N 2 - [3-（甲基氨基羰基亚甲基氧基）苯基] 嘧啶二胺
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Application No.: US12676075Application Date: 2008-08-27
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Publication No.: US08193181B2Publication Date: 2012-06-05
- Inventor: Stefan Colin John Taylor
- Applicant: Stefan Colin John Taylor
- Applicant Address: US CA South San Francisco
- Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Klarquist Sparkman, LLP
- Agent Travis Young
- International Application: PCT/IB2008/002288 WO 20080827
- International Announcement: WO2009/031011 WO 20090312
- Main IPC: C07D413/12
- IPC: C07D413/12 ; A61K31/538
![Xinafoate salt of N4-(2,2-difluoro-4H-benzo[1,4]oxazin-3-one)-6-yl]-5-fluoro-N2-[3-(methylaminocarbonylmethyleneoxy) phenyl]2,4-pyrimidinediamine](/images/no_image.jpg)
Abstract:
The present invention relates to the xinafoate salt of N4-[(2,2-difluoro-4H-benzo[1,4]oxazin-3-one)-6-yl]-5-fluoro-N2-[3-(methylaminocarbonylmethyleneoxy)phenyl]-2,4-pyrimidinediamine. This compound is a suitable drug substance and is useful in the treatment of conditions including asthma.
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