Methods and apparatus for matching image metadata to a profile database to determine image processing parameters are described. In embodiments, image metadata may be used to match input images against a profile database. For example, camera make and model information and/or lens make and model information may be retrieved from the image metadata corresponding to an input image and used to locate a best match profile in the profile database. Additional custom data may then be retrieved from the located profile to perform processing that may be optimized for a specific camera and lens that captured the images, and in some cases for particular camera settings. The profile database may be generated via a calibration process applied to each of a plurality of camera/lens combinations. In one embodiment, the additional custom data may be adjusted or scaled to account for differences in cameras, lenses, or settings.