The invention is directed to a method and system for supporting multiple time division duplexed (TDD) based wireless services or frequency division duplexed (FDD) wireless services on a Distributed Antenna System (DAS). A DAS can support a many wireless services, including voice and data services using the same physical equipment. TDD based services use a common clock signal to synchronize the components of the DAS for transmission and reception of TDD signals. In accordance with the invention, the DAS can include a GPS receiver which can extract a timing signal (such as a 1 pps signal) from a GPS signal and distribute the timing signal to any and all components of the DAS to enable synchronization of the components for transmitting and receiving TDD signals. The GPS receiver can be part of the interface that connects a TDD based service to the DAS or separate component of the DAS. In accordance with the invention, the DAS can distribute a reference clock signal to all of the components of the DAS in order to maintain zero frequency shift while manipulating with the carrier frequencies of the various wireless services carried by the DAS. In addition, and in accordance with the invention, two analog architectures for better integration between the services sources (BTS) and the DAS are disclosed.