The present invention is directed to a process of applying a solvent-based coating composition on a substrate to produce a multi-layer coating thereon. The binder component of the composition includes at least one hydroxy-functional polyether obtained from at least one polyol having at least three hydroxyl groups and at least one monoglycidyl ester of a branched monocarboxylic acid. The crosslinking component of the composition includes at least one cross-linking agent that is capable of entering into a cross-linking reaction with the hydroxyl groups of- the hydroxy-functional polyether. The process further includes curing the multi-layer coating. The process is well suited for producing clear coats and pigmented topcoats in automotive refinishing.