发明授权
US08198054B2 Method for the chemo-selective enzymatic hydrolysis if a diester compound for preparing a monoester monoacid compound
有权
用于制备单酯一酸化合物的二酯化合物的化学选择性酶水解的方法
- 专利标题： Method for the chemo-selective enzymatic hydrolysis if a diester compound for preparing a monoester monoacid compound
- 专利标题（中）： 用于制备单酯一酸化合物的二酯化合物的化学选择性酶水解的方法
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申请号： US12523602申请日： 2008-01-22
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公开(公告)号： US08198054B2公开(公告)日： 2012-06-12
- 发明人: Alain Burgos , Jean-Claude Caille , Michelle Lorraine-Gradley
- 申请人： Alain Burgos , Jean-Claude Caille , Michelle Lorraine-Gradley
- 申请人地址： FR Avrille GB Hertfordshire
- 专利权人： Zach System,Novacta Biosystem Limited
- 当前专利权人： Zach System,Novacta Biosystem Limited
- 当前专利权人地址： FR Avrille GB Hertfordshire
- 代理机构： Hamre, Schumann, Mueller & Larson, P.C.
- 优先权： FR0752792 20070122
- 国际申请： PCT/FR2008/050095 WO 20080122
- 国际公布： WO2008/110706 WO 20080918
- 主分类号： C12P7/40
- IPC分类号： C12P7/40
摘要：
This disclosure relates to the synthesis of the compound of formula (I) according to Scheme A below: in which R1, R2 and R3, which may be identical or different, represent, individually and independently, an alkyl group, characterized by an enzymatic hydrolysis reaction that involves placing the compound of formula (II) in contact with an enzyme that performs a chemoselective hydrolysis of only one of the two ester functions of the compound of formula (II) to obtain the compound of formula (I).
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