发明授权
US08198334B2 Methods for modulating macrophage proliferation in ocular disease using polyamine analogs
有权
使用多胺类似物调节眼部疾病巨噬细胞增殖的方法
- 专利标题： Methods for modulating macrophage proliferation in ocular disease using polyamine analogs
- 专利标题（中）： 使用多胺类似物调节眼部疾病巨噬细胞增殖的方法
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申请号： US11064781申请日： 2005-02-22
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公开(公告)号： US08198334B2公开(公告)日： 2012-06-12
- 发明人: Michael McGrath
- 申请人： Michael McGrath
- 申请人地址： US CA Burlingame
- 专利权人： Pathologica LLC
- 当前专利权人： Pathologica LLC
- 当前专利权人地址： US CA Burlingame
- 代理商 Dennis A. Bennett; Suman R. Mirmira
- 主分类号： A61K31/13
- IPC分类号： A61K31/13 ; A61K31/655
摘要：
Methods for modulating macrophage proliferation in an individual afflicted with or at risk for an ocular disease such as ARMD are provided. The methods employ a polyamine analog, or salt or protected derivative thereof. Macrophage proliferation has been implicated in a number of serious disorders, including ARMD. The invention also provides methods for aiding diagnosis and monitoring therapy of an ocular disease such as ARMD.
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