Invention Grant
US08198401B2 Peptides associated with HLA-DR MHC class II molecule and involved in rheumatoid arthritis
有权
与HLA-DR MHC II类分子相关并涉及类风湿性关节炎的肽
- Patent Title: Peptides associated with HLA-DR MHC class II molecule and involved in rheumatoid arthritis
- Patent Title (中): 与HLA-DR MHC II类分子相关并涉及类风湿性关节炎的肽
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Application No.: US10794227Application Date: 2004-03-05
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Publication No.: US08198401B2Publication Date: 2012-06-12
- Inventor: Jonathan Hill , Ewa Cairns , David Bell
- Applicant: Jonathan Hill , Ewa Cairns , David Bell
- Applicant Address: CA London, Ontario
- Assignee: London Health Sciences Centre Research Inc.
- Current Assignee: London Health Sciences Centre Research Inc.
- Current Assignee Address: CA London, Ontario
- Agency: Knobbe Martens Olson & Bear LLP
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C07K2/00
Abstract:
Antigenic peptides that bind to MHC Class II molecules with the shared epitope referred to as HLA-DR molecules are disclosed. More specifically, are citrullinated antigenic peptides having an increased affinity for HLA-DR molecules and associated with Rheumatoid Arthritis. These novel peptides provide the basis for new methods of diagnosis and treatment of Rheumatoid Arthritis.
Public/Granted literature
- US20090010943A1 Peptides associated with HLA-DR MHC class II molecule and involved in Rheumatoid arthritis Public/Granted day:2009-01-08
Information query
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