发明授权
- 专利标题： Phosphonic acid compounds as inhibitors of serine proteases
- 专利标题（中）： 膦酸化合物作为丝氨酸蛋白酶的抑制剂
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申请号： US12288998申请日： 2008-10-24
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公开(公告)号： US08198440B2公开(公告)日： 2012-06-12
- 发明人: Michael N. Greco , Harold R. Almond, Jr. , Michael J. Hawkins , Eugene Powell
- 申请人： Michael N. Greco , Harold R. Almond, Jr. , Michael J. Hawkins , Eugene Powell
- 申请人地址： US NJ Raritan
- 专利权人： Ortho-McNeil Pharmaceutical, Inc.
- 当前专利权人： Ortho-McNeil Pharmaceutical, Inc.
- 当前专利权人地址： US NJ Raritan
- 代理商 Yuriy P. Stercho
- 主分类号： C07F9/6509
- IPC分类号： C07F9/6509 ; C07D241/04 ; A61K31/495
摘要：
The present invention is directed to phosphonic acid compounds useful as serine protease inhibitors, compositions thereof and methods for treating inflammatory and serine protease mediated disorders.