发明授权
- 专利标题： 3-arylamino pyridine derivatives
- 专利标题（中）： 3-芳基氨基吡啶衍生物
-
申请号： US13112490申请日： 2011-05-20
-
公开(公告)号： US08198457B2公开(公告)日： 2012-06-12
- 发明人: Ulrich Abel , Holger Deppe , Achim Feurer , Ulrich Grädler , Kerstin Otte , Renate Sekul , Meinolf Thiemann , Andreas Goutopoulos , Matthias Schwarz , Xuliang Jiang
- 申请人： Ulrich Abel , Holger Deppe , Achim Feurer , Ulrich Grädler , Kerstin Otte , Renate Sekul , Meinolf Thiemann , Andreas Goutopoulos , Matthias Schwarz , Xuliang Jiang
- 申请人地址： CH Coinsins, Vaud
- 专利权人： Merck Serono S.A.
- 当前专利权人： Merck Serono S.A.
- 当前专利权人地址： CH Coinsins, Vaud
- 代理机构： Hamilton, Brook, Smith & Reynolds, P.C.
- 优先权： EP04024967 20041020
- 主分类号： C07D213/72
- IPC分类号： C07D213/72 ; C07D211/70 ; A01N43/58
摘要：
The invention provides novel, substituted 3-arylamino pyridine compounds pharmaceutically acceptable salts, solvates and prodrug compounds thereof, wherein W, R1, R2, R9, R10, R11, R12, R13, R14 are as defined in the specification. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer, restenosis and inflammation. Also disclosed is the use of such compounds in the treatment of hyperproliferative diseases in mammals, especially humans, and pharmaceutical compositions containing such compounds.
公开/授权文献
- US20110224192A1 3-Arylamino Pyridine Derivatives 公开/授权日：2011-09-15
信息查询
