发明授权
- 专利标题： Methods of controlling proliferation and differentiation of stem and progenitor cells
- 专利标题（中）： 控制干细胞和祖细胞增殖和分化的方法
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申请号： US12899268申请日： 2010-10-06
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公开(公告)号： US08202724B2公开(公告)日： 2012-06-19
- 发明人: Tony Peled , Eitan Fibach , Avi Treves
- 申请人： Tony Peled , Eitan Fibach , Avi Treves
- 申请人地址： IL Jerusalem IL Jerusalem
- 专利权人： Gamida Cell Ltd.,Hadasit Medical Research Services and Development Ltd.
- 当前专利权人： Gamida Cell Ltd.,Hadasit Medical Research Services and Development Ltd.
- 当前专利权人地址： IL Jerusalem IL Jerusalem
- 代理机构： Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- 代理商 Ivor R. Elrifi; Matthew Pavao
- 主分类号： C12N5/06
- IPC分类号： C12N5/06 ; C12N5/08 ; C12N5/00
摘要：
A method of ex-vivo expanding a population of stem cells, while at the same time inhibiting differentiation of the stem cells. The method comprises ex-vivo providing the stem cells with conditions for cell proliferation and with at least one copper chelator in an amount and for a time period for permitting the stem cells to proliferate and, at the same time, for reducing a capacity of the stem cells to differentiate.
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