发明授权
- 专利标题： Compounds and compositions as protein kinase inhibitors
- 专利标题（中）： 化合物和组合物作为蛋白激酶抑制剂
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申请号： US12444129申请日： 2007-09-24
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公开(公告)号： US08202876B2公开(公告)日： 2012-06-19
- 发明人: Pamela Albaugh , Gregory B. Chopiuk , Qiang Ding , Shenlin Huang , Zuosheng Liu , Shifeng Pan , Pingda Ren , Xia Wang , Xing Wang , Yongping Xie , Chengzhi Zhang , Qiong Zhang , Guobao Zhang , Daniel Poon , Paul Renhowe , Martin Sendzik
- 申请人： Pamela Albaugh , Gregory B. Chopiuk , Qiang Ding , Shenlin Huang , Zuosheng Liu , Shifeng Pan , Pingda Ren , Xia Wang , Xing Wang , Yongping Xie , Chengzhi Zhang , Qiong Zhang , Guobao Zhang , Daniel Poon , Paul Renhowe , Martin Sendzik
- 申请人地址： BM Hamilton CH Basel
- 专利权人： IRM LLC,Novartis AG
- 当前专利权人： IRM LLC,Novartis AG
- 当前专利权人地址： BM Hamilton CH Basel
- 代理机构： Genomics Institute of the Novartis Research Foundation
- 代理商 Daniel E. Raymond
- 国际申请： PCT/US2007/079340 WO 20070924
- 国际公布： WO2008/042639 WO 20080410
- 主分类号： C07D401/00
- IPC分类号： C07D401/00 ; C07D403/00 ; C07D405/00 ; C07D409/00 ; C07D411/00 ; C07D413/00 ; C07D417/00 ; C07D419/00 ; C07D231/00 ; C07D403/02 ; A01N43/56 ; A61K31/415
摘要：
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, ARG, BCR-Abl, BRK, EphB, Fms, Fyn, KDR, c-Kit, LCK, PDGF-R, b-Raf, c-Raf, SAPK2, Src, Tie2 and TrkB kinases.
公开/授权文献
- US20100029605A1 COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS 公开/授权日：2010-02-04
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