Invention Grant
US08202883B2 Substituted pyrido[2,3-b]pyrazine compounds as modulators of tyrosine kinases
失效
取代的吡啶并[2,3-b]吡嗪化合物作为酪氨酸激酶的调节剂
![Substituted pyrido[2,3-b]pyrazine compounds as modulators of tyrosine kinases](/docs/US/2012-06-19/US08202883B2/abs.jpg.600x600.jpg)
- Patent Title: Substituted pyrido[2,3-b]pyrazine compounds as modulators of tyrosine kinases
- Patent Title (中): 取代的吡啶并[2,3-b]吡嗪化合物作为酪氨酸激酶的调节剂
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Application No.: US12117942Application Date: 2008-05-09
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Publication No.: US08202883B2Publication Date: 2012-06-19
- Inventor: Matthias Gerlach , Irene Seipelt , Eckhard Guenther , Emmanuel Polymeropoulos , Tilmann Schuster , Eckhard Claus
- Applicant: Matthias Gerlach , Irene Seipelt , Eckhard Guenther , Emmanuel Polymeropoulos , Tilmann Schuster , Eckhard Claus
- Applicant Address: DE Frankfurt am Main
- Assignee: Aeterna Zentaris GmbH
- Current Assignee: Aeterna Zentaris GmbH
- Current Assignee Address: DE Frankfurt am Main
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- Priority: EP07107976 20070510
- Main IPC: A61K31/44
- IPC: A61K31/44
![Substituted pyrido[2,3-b]pyrazine compounds as modulators of tyrosine kinases](/abs-image/US/2012/06/19/US08202883B2/abs.jpg.150x150.jpg)
Abstract:
The invention relates to pyrido[2,3-b]pyrazine compounds of formulae (Ia) and (Ib) which have activity to the modulation of misdirected cellular signal transduction processes such as tyrosine kinases, serine/threonine kinases and/or lipid kinases, their preparation and use as medicaments, especially for the treatment of malignant disorders and other disorders based on pathological cell proliferations:
Public/Granted literature
- US20090275534A1 NOVEL PYRIDOPYRAZINE DERIVATIVES, PROCESS OF MANUFACTURING AND USES THEREOF Public/Granted day:2009-11-05
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