发明授权
US08203019B2 Crystalline solid and amorphous forms of (−)- halofenate and methods related thereto
有权
（ - ） - 卤化物的结晶固体和无定形形式及其相关方法
- 专利标题： Crystalline solid and amorphous forms of (−)- halofenate and methods related thereto
- 专利标题（中）： （ - ） - 卤化物的结晶固体和无定形形式及其相关方法
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申请号： US11408609申请日： 2006-04-20
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公开(公告)号： US08203019B2公开(公告)日： 2012-06-19
- 发明人: Edward D. Daugs , Eric J. Hagen , Jason A. Hanko , David H. Louks
- 申请人： Edward D. Daugs , Eric J. Hagen , Jason A. Hanko , David H. Louks
- 申请人地址： US CA Hayward US TX San Antonio
- 专利权人： Metabolex, Inc.,DiaTex, Inc.
- 当前专利权人： Metabolex, Inc.,DiaTex, Inc.
- 当前专利权人地址： US CA Hayward US TX San Antonio
- 代理机构： Hamilton DeSanctis & Cha, LLP
- 主分类号： C07C69/76
- IPC分类号： C07C69/76 ; C07C69/63 ; C07C67/02 ; A61K31/235 ; A61K31/22
摘要：
The present invention provides crystalline solid and amorphous forms of (−)-halofenate. The crystalline solid forms may be used in various pharmaceutical compositions, and are particularly effective for the prevention and/or treatment of conditions associated with blood lipid deposition in a mammal, particularly those diseases related to Type 2 diabetes and hyperlipidemia. The invention also relates to a method for preventing or treating Type 2 diabetes and hyperlipidemia in a mammal comprising the step of administering a therapeutically effective amount of crystalline solid and amorphous forms of (−)-halofenate.
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