A wireless node location mechanism that defines a search region to optimize the computations associated with estimating the location of a given wireless node. According to one implementation, a coverage map associated with each radio receiver that records signal strength data is defined out to a threshold signal strength level. Before computing the estimated location of a given wireless nodes, a search region is defined based on the intersection of the coverage maps associated with each radio receiver that detects the wireless node. Some implementations use information provided by the fact that certain radio receivers did not detect the wireless node to further optimize the location estimate. By defining a search region, which is a generally small area relative to the space encompassed by an entire RF environment, the present invention provides several advantages, such as reducing the processing time and/or power to compute estimated locations for wireless nodes.