Systems and methods for cache defeat detection are disclosed. Moreover, systems and methods for caching of content addressed by identifiers intended to defeat cache are further disclosed. In one aspect, embodiments of the present disclosure include a system for optimizing resources in a mobile network, by for example performing one or more of, identifying a parameter in an identifier used in multiple polling requests to a given content source; means for, detecting that the parameter in the identifier changes for each of the polling requests; determining whether responses received from the given content source are the same for each of the multiple polling requests; and/or caching the responses on the mobile device in response to determining that the responses received for the given content source are the same.