发明授权
- 专利标题: Hafnia phytase variants
- 专利标题(中): Hafnia植酸酶变体
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申请号: US12568312申请日: 2009-09-28
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公开(公告)号: US08206962B2公开(公告)日: 2012-06-26
- 发明人: Soeren Flensted Lassen , Leonardo De Maria , Esben Peter Friis , Tomoko Matsui , Allan Noergaard , Lars Kobberoee Skov , Jesper Vind
- 申请人: Soeren Flensted Lassen , Leonardo De Maria , Esben Peter Friis , Tomoko Matsui , Allan Noergaard , Lars Kobberoee Skov , Jesper Vind
- 申请人地址: DK Bagsvaerd
- 专利权人: Novozymes A/S
- 当前专利权人: Novozymes A/S
- 当前专利权人地址: DK Bagsvaerd
- 代理商 Elias Lambiris
- 优先权: EP08165245 20080926
- 主分类号: C12N9/14
- IPC分类号: C12N9/14 ; C12Q1/34 ; C07H21/04
摘要:
The present invention relates to phytases having at least 76% identity to a phytase derived from Hafnia alvei and comprises at least one modification in the amino acid sequence thereof. These phytase variants have modified, preferably improved, properties, such as, reduced protease sensibility, preferably they exhibit improved properties in respect of thermal performance, such as heat-stability (temperature stability, thermostability), steam stability, pelleting stability and/or temperature profile; and/or protease stability, in particular pepsin stability, pH profile, specific activity, substrate specificity, performance in animal feed (such as an improved release and/or degradation of phytate), susceptibility to glycation, and/or glycosylation pattern. The invention also relates to DNA encoding these phytases, methods of their production, as well as the use thereof, e.g., in animal feed and animal feed additives.
公开/授权文献
- US20100083392A1 HAFNIA PHYTASE VARIANTS 公开/授权日:2010-04-01
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