发明授权
- 专利标题： Immobilization of membrane proteins onto supports via an amphiphile
- 专利标题（中）： 通过两亲物将膜蛋白固定在载体上
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申请号： US12514656申请日： 2007-11-13
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公开(公告)号： US08207263B2公开(公告)日： 2012-06-26
- 发明人: Jean-Luc Popot , Delphine Charvolin , Fabrice Giusti
- 申请人： Jean-Luc Popot , Delphine Charvolin , Fabrice Giusti
- 申请人地址： FR Paris FR Paris
- 专利权人： Centre National de la Recherche Scientifique (CNRS),Universite Paris 7—Denis Diderot
- 当前专利权人： Centre National de la Recherche Scientifique (CNRS),Universite Paris 7—Denis Diderot
- 当前专利权人地址： FR Paris FR Paris
- 代理机构： Pepper Hamilton LLP
- 优先权： FR0609882 20061113
- 国际申请： PCT/EP2007/062277 WO 20071113
- 国际公布： WO2008/058963 WO 20080522
- 主分类号： A61K47/48
- IPC分类号： A61K47/48 ; C08G63/48 ; C08G63/91 ; C08L89/00 ; D21H19/50 ; C08F20/00 ; C08F22/38 ; C08F26/00 ; C08F120/00 ; C08F220/54 ; C08F220/70 ; C08F222/38 ; C08F226/02 ; C08F236/00 ; C12Q1/00
摘要：
The invention pertains to the field of membrane protein immobilization onto supports. It relates to a product comprising a support and at least one membrane protein attached to the surface thereof, characterized in that said membrane protein is attached to said support using an amphiphilic molecule with which said membrane protein is complexed. It also relates to a process for preparing such product, as well as to various applications in the fields of diagnosis, drug design and biotechnologies. It further relates to a kit, together with a functionalized amphiphilic molecule, for preparing a product according to the invention comprising a support and an amphiphilic molecule, wherein the amphiphilic molecule and the support interact through a hydrophobic bond, an ionic bond, a specific bond or a covalent bond.
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