发明授权
- 专利标题: Antibody antagonists of interleukin-13 receptor α1
- 专利标题(中): 白细胞介素-13受体α1的抗体拮抗剂
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申请号: US12445759申请日: 2007-10-19
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公开(公告)号: US08207304B2公开(公告)日: 2012-06-26
- 发明人: Andrew Donald Nash , Louis Jerry Fabri , Dennis Zaller , William R. Strohl , Zhiqiang An
- 申请人: Andrew Donald Nash , Louis Jerry Fabri , Dennis Zaller , William R. Strohl , Zhiqiang An
- 申请人地址: AU Parkville
- 专利权人: CSL Limited
- 当前专利权人: CSL Limited
- 当前专利权人地址: AU Parkville
- 代理机构: Licata & Tyrrell P.C.
- 国际申请: PCT/US2007/081889 WO 20071019
- 国际公布: WO2008/049098 WO 20080424
- 主分类号: C07K16/00
- IPC分类号: C07K16/00 ; C12N15/13
摘要:
Antibody antagonists of human interleukin-13 receptor alpha 1 are disclosed. The antibody molecules are useful in the inhibition of IL-13Rα1-mediated activities and, accordingly, present desirable antagonists for the use in the treatment of conditions associated with hIL-13Rα activity. The present invention also discloses nucleic acid encoding said antibody molecules, vectors, host cells, and compositions comprising the antibody molecules. Methods of using the antibody molecules for inhibiting or antagonizing IL-13Rα1-mediated activities are also disclosed.
公开/授权文献
- US20090285799A1 Antibody Antagonists of Interleukin-13 Receptor Alpha1 公开/授权日:2009-11-19
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