A non-volatile memory cell and associated programming methods that allow for integration of non-volatile memory with other CMOS integrated circuitry utilizing standard CMOS processing. The non-volatile memory cell includes an antifuse element having a programming node and a capacitor element coupled to the antifuse element and configured to provide one or more voltage pulses to the programming node. The antifuse element is configured to have a changed resistivity after the programming node is subjected to the one or more voltage pulses, the change in resistivity representing a change in logic state. The antifuse element comprises a MOS transistor, its gate being coupled to one of the programming node and a control node, and its source and drain being coupled to the other one of the programming node and the control node. The MOS transistor is formed in a well and the source, drain and well are coupled to the same voltage level.