A tube holder for a tube filling machine includes a cup-shaped housing having a tube receptacle that opens towards the top and into which one end area of a tube can be inserted. At least one vertical groove is formed in the area of the inner wall of the tube receptacle into which a clamping element is inserted, wherein the clamping element can be radially displaced substantially perpendicularly to the longitudinal central axis of the tube receptacle and is pivotably disposed about a pivot axis that extends substantially tangentially relative to the inner wall of the tube receptacle. A clamping force that acts radially from the outside onto the inserted tube can be applied by the clamping element under the action of upper and lower spring elements. The pivot axis is thereby formed on a pivot bearing which permits radial displacement of the pivot axis.