Systems and methods of providing opportunistic security for physical communication channels are disclosed. One disclosed method is for opportunistic secure communication on a main channel between a sender device and a receiver device when an eavesdropper device is listening on an eavesdropper channel. This example method includes transmitting, in a first time period in which signal quality on the main channel is better than signal quality on the eavesdropper channel, symbols that are randomly selected from a set of symbols. The method also includes transmitting, in a second time period in which signal quality on the main channel is not better than signal quality on the eavesdropper channel, coding information associated with the randomly selected symbols. The method also includes reconciling the randomly selected symbols using the coding information.