发明授权
- 专利标题: Spiroindolinone pyrrolidines
- 专利标题(中): 螺吲哚啉酮吡咯烷
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申请号: US13072872申请日: 2011-03-28
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公开(公告)号: US08217044B2公开(公告)日: 2012-07-10
- 发明人: Xin-Jie Chu , Qingjie Ding , Nan Jiang , Jing Zhang , Zhuming Zhang
- 申请人: Xin-Jie Chu , Qingjie Ding , Nan Jiang , Jing Zhang , Zhuming Zhang
- 申请人地址: US NJ Nutley
- 专利权人: Hoffmann-La Roche Inc.
- 当前专利权人: Hoffmann-La Roche Inc.
- 当前专利权人地址: US NJ Nutley
- 代理商 George W. Johnston; Patricia S. Rocha-Tramaloni
- 主分类号: A61K31/4025
- IPC分类号: A61K31/4025 ; A61K31/407 ; A61K31/4155 ; A61K31/4178 ; A61K31/427 ; A61K31/4439 ; A61K31/497 ; A61K31/501 ; A61K31/506 ; C07D209/54 ; C07D401/14 ; C07D403/14 ; C07D405/14 ; C07D417/14
摘要:
There are provided compounds of the formula wherein X, Y and R1 to R8 are as described herein and the enantiomers and pharmaceutically acceptable salts and esters thereof which compounds have anticancer activity.
公开/授权文献
- US20110269809A1 SPIROINDOLINONE PYRROLIDINES 公开/授权日:2011-11-03
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