An image pickup system includes a base, a frame, an image pickup device, a receiving structure, a marking element and a switching element. The frame is connected to the base. The image pickup device is disposed on the frame. The receiving structure is disposed in the base. The frame is rotatable with respect to the base, so that the image pickup device is moved to an optimal shooting position. The marking element indicates that the image pickup device is at the optimal shooting position. When the switching element is triggered, the target object placed in the receiving structure will be shot by the image pickup device.