发明授权
US08222266B2 Azabicyclo [3.1.0] hexyl derivatives as modulators of dopamine D3 receptors
失效
氮杂双环[3.1.0]己基衍生物作为多巴胺D3受体的调节剂
![Azabicyclo [3.1.0] hexyl derivatives as modulators of dopamine D3 receptors](/docs/US/2012-07-17/US08222266B2/abs.jpg.600x600.jpg)
- 专利标题： Azabicyclo [3.1.0] hexyl derivatives as modulators of dopamine D3 receptors
- 专利标题（中）： 氮杂双环[3.1.0]己基衍生物作为多巴胺D3受体的调节剂
-
申请号： US12295304申请日： 2007-03-30
-
公开(公告)号： US08222266B2公开(公告)日： 2012-07-17
- 发明人: Barbara Bertani , Anna Checchia , Romano Di Fabio , Gabriella Gentile , Fabrizio Micheli , Alessandra Pasquarello , Silvia Terreni
- 申请人： Barbara Bertani , Anna Checchia , Romano Di Fabio , Gabriella Gentile , Fabrizio Micheli , Alessandra Pasquarello , Silvia Terreni
- 申请人地址： GB Greenford, Middlesex
- 专利权人： Glaxo Group Limited
- 当前专利权人： Glaxo Group Limited
- 当前专利权人地址： GB Greenford, Middlesex
- 代理商 Bonnie L. Deppenbrock
- 优先权： GB0607892.7 20060403; GB0703397.0 20070221
- 国际申请： PCT/EP2007/053117 WO 20070330
- 国际公布： WO2007/113260 WO 20071011
- 主分类号： C07D403/06
- IPC分类号： C07D403/06 ; A61K31/513
![Azabicyclo [3.1.0] hexyl derivatives as modulators of dopamine D3 receptors](/abs-image/US/2012/07/17/US08222266B2/abs.jpg.150x150.jpg)
摘要：
The present invention relates to certain azabicyclo compounds of formula (I)′: wherein the various groups are defined herein and that are modulators of dopamine D3 receptors, e.g. to treat drug dependency, as antipsychotic agents, to treat obsessive compulsive spectrum disorders, or premature ejaculation.