发明授权
US08222407B2 Mutilin derivative having heterocyclic aromatic ring carboxylic acid structure in substituent at 14-position
失效
在14位的取代基中具有杂环芳环羧酸结构的Mutilin衍生物
- 专利标题： Mutilin derivative having heterocyclic aromatic ring carboxylic acid structure in substituent at 14-position
- 专利标题（中）： 在14位的取代基中具有杂环芳环羧酸结构的Mutilin衍生物
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申请号： US12451656申请日： 2008-05-23
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公开(公告)号： US08222407B2公开(公告)日： 2012-07-17
- 发明人: Yasumichi Fukuda , Masanori Takadoi , Yoshikazu Asahina , Taro Sato , Haruaki Kurasaki , Hiroyuki Ebisu , Masaya Takei , Hideyuki Fukuda
- 申请人： Yasumichi Fukuda , Masanori Takadoi , Yoshikazu Asahina , Taro Sato , Haruaki Kurasaki , Hiroyuki Ebisu , Masaya Takei , Hideyuki Fukuda
- 申请人地址： JP Tokyo
- 专利权人： Kyorin Pharmaceutical Co., Ltd.
- 当前专利权人： Kyorin Pharmaceutical Co., Ltd.
- 当前专利权人地址： JP Tokyo
- 代理机构： Wenderoth, Lind & Ponack, L.L.P.
- 优先权： JPP2007-137473 20070524
- 国际申请： PCT/JP2008/059535 WO 20080523
- 国际公布： WO2008/143343 WO 20081127
- 主分类号： C07D498/04
- IPC分类号： C07D498/04 ; C07D401/10 ; C07D413/14 ; C07D471/04
摘要：
To provide a novel mutilin derivative having a substitution at the 14-position, which is a novel mutilin analogue exhibiting a potent and broad antimicrobial action against Gram-positive bacteria and Gram-negative bacteria including various drug-resistant bacteria, and which is expected to be useful as an agent for treating infectious diseases. A mutilin derivative represented by the following general formula (1): or a pharmaceutically acceptable addition salt thereof.