An inter-cell interference coordination method comprises: measuring an interference over thermal noise of a first subcarrier resource block in an uplink direction and obtaining an interference over thermal noise measurement value by a first base station; judging whether a first high interference indicating message is received from a second base station when the interference over thermal noise measurement value is larger than a first preset threshold value by the first base station; sending an overload indicator message to the second base station which has sent the high interference indicating message or shielding the first subcarrier resource block by the first base station when the first high interference indicating message is received; and sending the overload indicator message to base stations to which all the neighboring cells belong by the first base station when the first high interference indicating message is not received. The overhead at X2 interface is reduced according to the present invention.