发明授权
- 专利标题： 2,4-disubsituted thiazoles and pharmaceutical compositions thereof
- 专利标题（中）： 2,4-二取代噻唑及其药物组合物
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申请号： US12541865申请日： 2009-08-14
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公开(公告)号： US08227495B2公开(公告)日： 2012-07-24
- 发明人: Xin Chen , Peng Cheng , L. Edward Clemens , Jeffrey D. Johnson , Jingyuan Ma , Alison Murphy , Imad Nashashibi , Christopher J. Rabbat , Jiangao Song , Maria E. Wilson , Yan Zhu , Zuchun Zhao
- 申请人： Xin Chen , Peng Cheng , L. Edward Clemens , Jeffrey D. Johnson , Jingyuan Ma , Alison Murphy , Imad Nashashibi , Christopher J. Rabbat , Jiangao Song , Maria E. Wilson , Yan Zhu , Zuchun Zhao
- 申请人地址： US CA Hayward
- 专利权人： Metabolex Inc.
- 当前专利权人： Metabolex Inc.
- 当前专利权人地址： US CA Hayward
- 代理机构： Foley & Lardner LLP
- 主分类号： A61K31/425
- IPC分类号： A61K31/425
摘要：
The present disclosure provides 2,4-disubstituted thiazoles of the general structure shown below that are agonists of G-protein coupled receptor (IC-GPCR2). Also, provided are compositions comprising these compounds as well as methods for using these compounds in a variety of applications including diabetes and metabolic disorders.
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