发明授权
- 专利标题: Polymorphic form of rotigotine and process for production
- 专利标题(中): 罗替戈汀的多晶型和生产工艺
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申请号: US12324166申请日: 2008-11-26
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公开(公告)号: US08232414B2公开(公告)日: 2012-07-31
- 发明人: Hans-Michael Wolff , Luc Quere , Jens Riedner
- 申请人: Hans-Michael Wolff , Luc Quere , Jens Riedner
- 申请人地址: DE Monheim
- 专利权人: UCB Pharma GmbH
- 当前专利权人: UCB Pharma GmbH
- 当前专利权人地址: DE Monheim
- 代理机构: Harness, Dickey & Pierce, P.L.C.
- 优先权: EP07121795 20071128; EP08166576 20081014
- 主分类号: C07D333/20
- IPC分类号: C07D333/20
摘要:
The present invention relates to a novel polymorphic form of rotigotine characterized by at least one of the following powder X-ray diffraction peaks: 12.04, 13.68, 17.72 and 19.01±0.2 (° 2θ), measured with a Cu—Kα irradiation (1.54060 Å), and a process for production thereof, which is useful for the manufacture of a stable medicament for treating or alleviating symptoms of Parkinson's disease and other dopamine-related disorders.
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