发明授权
- 专利标题： Protein showing enhanced expression in cancer cells
- 专利标题（中）： 蛋白质在癌细胞中表达增强
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申请号： US12842971申请日： 2010-07-23
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公开(公告)号： US08236510B2公开(公告)日： 2012-08-07
- 发明人: Aya Jakobovits , Mary Faris , Arthur B. Raitano , Robert Kendall Morrison , Douglas Saffran , Wangmao Ge , Pia M. Challita-Eid
- 申请人： Aya Jakobovits , Mary Faris , Arthur B. Raitano , Robert Kendall Morrison , Douglas Saffran , Wangmao Ge , Pia M. Challita-Eid
- 申请人地址： US CA Santa Monica
- 专利权人： Agensys, Inc.
- 当前专利权人： Agensys, Inc.
- 当前专利权人地址： US CA Santa Monica
- 代理机构： Morrison & Foerster LLP
- 主分类号： G01N33/53
- IPC分类号： G01N33/53
摘要：
A novel gene (designated 101P3A11 or PHOR-1) and its encoded protein, and variants thereof, are described wherein 101P3A11 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 101P3A11 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 101P3A11 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 101P3A11 can be used in active or passive immunization.
公开/授权文献
- US20100291126A1 PROTEIN SHOWING ENHANCED EXPRESSION IN CANCER CELLS 公开/授权日：2010-11-18