发明授权
- 专利标题： Tricyclic spiro derivatives as CRTH2 modulators
- 专利标题（中）： 三环螺衍生物作为CRTH2调节剂
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申请号： US11919471申请日： 2006-05-23
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公开(公告)号： US08236963B2公开(公告)日： 2012-08-07
- 发明人: Matthias Schwarz , Eric Sebille , Christophe Cleva , Cedric Merlot , Dennis Church , Patrick Page , Jacqueline A. Macritchie , John Frederick Atherall , Stefano Crosignani , Doris Pupowicz
- 申请人： Matthias Schwarz , Eric Sebille , Christophe Cleva , Cedric Merlot , Dennis Church , Patrick Page , Jacqueline A. Macritchie , John Frederick Atherall , Stefano Crosignani , Doris Pupowicz
- 申请人地址： CH Vaud
- 专利权人： Merck Serono SA
- 当前专利权人： Merck Serono SA
- 当前专利权人地址： CH Vaud
- 代理机构： EMD Serono Research Institute
- 优先权： EP05104428 20050524
- 国际申请： PCT/EP2006/062545 WO 20060523
- 国际公布： WO2006/125784 WO 20061130
- 主分类号： C07D277/20
- IPC分类号： C07D277/20 ; C07D271/06 ; C07D417/14 ; C07D487/10 ; C07D261/06 ; A61K31/44 ; A61K31/431 ; A61K31/4184 ; A61K31/4196 ; A61K31/41
摘要：
The present invention is related to the use of spiro derivatives of Formula (I) for the treatment and/or prevention of allergic diseases, inflammatory dermatoses and other diseases with an inflammatory component. Specifically, the present invention is related to the use of spiro derivatives for the modulation of CRTH2 activity.
公开/授权文献
- US20090318486A1 Tricyclic spiro derivatives as CRTH2 modulators 公开/授权日：2009-12-24
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