A medical article, such as a catheter, is secured to a patient with a support structure and a plurality of attachment/receiving surfaces that permit the catheter to be reoriented in multiple positions relative to the support structure including rotating the catheter about a longitudinal axis. The support structure may be an anchor pad, strap, or other structure. The plurality of attachment/receiving surfaces may be hook and loop type fasteners that are adhered to the catheter body and to the support structure. The placement of the support structure on the patient is not critical as the catheter position is not fixed relative to the support structure.