A system and method for remote acquisition and delivery of goods includes a server in communication with customer computers, such as through a user interface via the internet. The server can store customer information including billing information, and may include a real-time video processor. A mobile delivery system in communication with the server includes an energy efficient vehicle, a real-time video device, a global positioning system, a communication device and a printer. In use, a customer communicates with a mobile delivery agent via the real-time video device and the communication device to remotely acquire a product. Once acquired, the delivery agent delivers the product to a designated delivery location. The real-time video device can be utilized during the entire transaction. The system preferably includes a processor for optimizing system efficiencies, including selecting a delivery agent based on the product, pick-up location and delivery site.