A waterproof and water vapor-permeable shoe, including a bottom shoe part with a sole perforated through from the tread toward a foot resting region, a top part surrounding the foot and including a vapor-permeable or perforated lining, a waterproof and vapor-permeable membrane surrounding the foot, and a vapor-permeable or perforated upper. The outer bottom portion of the top shoe part, which is superimposed on the perforated area of the sole, is constituted by a portion of the membrane. A vapor-permeable or perforated protective element for the portion of the membrane is provided below the portion of the membrane and above the tread of the sole. A water sealing region provided between the portion of the membrane and the sole, around the perforated area of the sole, separates flaps of the upper from the perforated area of the sole.