Invention Grant
- Patent Title: β-1,3-glucan-derived polyaldehyde/polyamine hydrogel
- Patent Title (中): -1,3-葡聚糖衍生的多醛/多胺水凝胶
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Application No.: US12734425Application Date: 2008-11-04
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Publication No.: US08246992B2Publication Date: 2012-08-21
- Inventor: Takeshi Nagasaki , Tatsuro Hayashi , Kenji Oohata , Kenichi Ishibashi , Toshio Suzuki , Yoshiro Furukawa
- Applicant: Takeshi Nagasaki , Tatsuro Hayashi , Kenji Oohata , Kenichi Ishibashi , Toshio Suzuki , Yoshiro Furukawa
- Applicant Address: JP Osaka JP Osaka
- Assignee: Osaka City University,Daiso Co., Ltd.
- Current Assignee: Osaka City University,Daiso Co., Ltd.
- Current Assignee Address: JP Osaka JP Osaka
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: JP2007-285087 20071101; JP2008-180178 20080710
- International Application: PCT/JP2008/070052 WO 20081104
- International Announcement: WO2009/057802 WO 20090507
- Main IPC: A61K9/14
- IPC: A61K9/14
Abstract:
The present invention provides a combination product which comprises: (1) a polyaldehyde obtained by introducing an aldehyde group into a branched glucose in a β-1,3-glucan, and (2) a polyamine obtained by increasing the molecular weight of a poly-L-lysine. The combination product according to the present invention is useful as a material for a tissue adhesive hydrogel which can be used as a hemostatic agent or the like which exhibits low risks for viral infections and the like, high biodegradability and biocompatibility, excellent safety, a good adhesion rate and a good adhesion strength.
Public/Granted literature
- US20100316719A1 B-1,3-GLUCAN-DERIVED POLYALDEHYDE/POLYAMINE HYDROGEL Public/Granted day:2010-12-16
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