Invention Grant
- Patent Title: Hydroxymethyl pyrrolidines as β3 adrenergic receptor agonists
- Patent Title (中): 羟基甲基吡咯烷作为3肾上腺素能受体激动剂
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Application No.: US12417239Application Date: 2009-04-02
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Publication No.: US08247415B2Publication Date: 2012-08-21
- Inventor: Richard Berger , Lehua Chang , Scott D. Edmondson , Stephen D. Goble , Sookhee Nicole Ha , Nam Fung Kar , Ihor E. Kopka , Bing Li , Gregori J. Morriello , Chris R. Moyes , Dong-Ming Shen , Liping Wang , Cheng Zhu
- Applicant: Richard Berger , Lehua Chang , Scott D. Edmondson , Stephen D. Goble , Sookhee Nicole Ha , Nam Fung Kar , Ihor E. Kopka , Bing Li , Gregori J. Morriello , Chris R. Moyes , Dong-Ming Shen , Liping Wang , Cheng Zhu
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Patricia A. Shatynski; Valerie J. Camara
- Main IPC: C07D237/30
- IPC: C07D237/30 ; C07D239/90 ; C07D221/02 ; C07D277/60 ; A61K31/502 ; A61K31/517 ; A61K31/435 ; A61K31/428 ; A61P13/10 ; A61P13/06

Abstract:
The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.
Public/Granted literature
- US20090253705A1 HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS Public/Granted day:2009-10-08
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