Invention Grant
US08247564B2 Compounds having BETA2 adrenergic receptor agonist and muscarinic receptor antagonist activity 失效
具有BETA2肾上腺素能受体激动剂和毒蕈碱受体拮抗剂活性的化合物

  • Patent Title: Compounds having BETA2 adrenergic receptor agonist and muscarinic receptor antagonist activity
  • Patent Title (中): 具有BETA2肾上腺素能受体激动剂和毒蕈碱受体拮抗剂活性的化合物
  • Application No.: US12903365
    Application Date: 2010-10-13
  • Publication No.: US08247564B2
    Publication Date: 2012-08-21
  • Inventor: Mathai MammenSarah Dunham
  • Applicant: Mathai MammenSarah Dunham
  • Applicant Address: US CA South San Francisco
  • Assignee: Theravance, Inc.
  • Current Assignee: Theravance, Inc.
  • Current Assignee Address: US CA South San Francisco
  • Agent Jeffrey A. Hagenah
  • Main IPC: C07D409/00
  • IPC: C07D409/00
Compounds having BETA2 adrenergic receptor agonist and muscarinic receptor antagonist activity
Abstract:
The invention is directed to compounds of formula I: wherein R1, R2, R3, R4, R5, R6, R7a, R7b, W, G1, G2, a, b, c, d and m are as defined in the specification, or a pharmaceutically acceptable salt or solvate or stereoisomer thereof. The invention is also directed to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.
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