Aspects relate to interference management in a multiple-input-multiple-output peer-to-peer network utilizing connection scheduling. When channel side information is available at both transmitter and receiver, both devices determine transmit/receiver beamforming vectors. Transmitter sends a first transmission request signal with first transmit beamforming vector and a second transmission request signal with second transmit beamforming vector in a transmission request block. Receiver estimates SINRs of the MIMO channels associated with the receive beamforming vectors and determines whether to return request response signals. Based on received request response signals, transmitter decides to transmit streams of data using the corresponding transmit beamforming vectors in the data burst. When channel side information is available only at receiver, transmitter sends one transmission request signal. Receiver estimates the SINRs of the MIMO channels associated with receive beamforming vectors using MMSE and/or successive interference cancellation (SIC), and returns request response signals in the request response block.